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CRISPector algorithm can spot potential off-target modifications and quantify translocations. Amit, I. et al. (2021) CRISPECTOR provides accurate estimation of
Chen, L. et al. (2021) Programmable genome editing with CRISPR-Cas9-directed base excision repair proteins Nature Communications.DOI: 10.1038/s41467-021-21559-9 Keywords: CRISPR, Base
Researchers from the University of Pennsylvania have developed a new CRISPR-based method to help trace the lineage and gene expression
In the lab of David Liu, a CRISPR base editor was successfully applied to correct mutations in the β-globin gene
CRISPR base editors delivered via a single infusion of lipid nanoparticles to the liver efficiently reduced expression of the PCSK9